Mauro LJ

ORCID: 0000-0003-4372-8299 · 3 papers in corpus
2023
Navigating a plethora of progesterone receptors: Comments on the safety/risk of progesterone supplementation in women with a history of breast cancer or at high-risk for developing breast cancer.
Steroids ·doi:10.1016/j.steroids.2023.109329

Progesterone and progestin agonists are potent steroid hormones. There are at least three major types of progesterone receptor (PR) families that interact with and respond to progesterone or progestin ligands. These receptors include ligand…

2023
Reevaluating the Role of Progesterone in Ovarian Cancer: Is Progesterone Always Protective?
Endocrine Reviews ·doi:10.1210/endrev/bnad018

Ovarian cancer (OC) represents a collection of rare but lethal gynecologic cancers where the difficulty of early detection due to an often-subtle range of abdominal symptoms contributes to high fatality rates. With the exception of BRCA1/2 …

2015
Progesterone action in breast, uterine, and ovarian cancers.
Journal of molecular endocrinology ·doi:10.1530/jme-14-0252

Progesterone and progesterone receptors (PRs) are essential for the development and cyclical regulation of hormone-responsive tissues including the breast and reproductive tract. Altered functions of PR isoforms contribute to the pathogenes…