Weidong Fei

No ORCID on file · 7 papers in corpus · active 2019-2026

Study types

  • article 2
  • other 2
  • peer-review 1
  • review 1

Condition tags

  • endometriosis 6
  • adenomyosis 2
  • infertility 1
other 2026
Synergistic RU486 and olaparib therapy enhances apoptosis in endometriosis by simultaneously targeting hormonal signalling and DNA repair
British journal of pharmacology ·doi:10.1111/bph.70360

BACKGROUND AND PURPOSE: Endometriosis is a chronic, hormone-dependent disorder characterized by ectopic implantation of endometrial tissue, often accompanied by pain and infertility. Although the progesterone receptor modulator RU486 is eff…

other 2025
Unraveling shared diagnostic genes and cellular microenvironmental changes in endometriosis and recurrent implantation failure through multi-omics analysis
Scientific reports ·doi:10.1038/s41598-025-93146-7

Endometriosis and Recurrent Implantation Failure (RIF) are both pivotal clinical issues within the realm of reproductive medicine, sharing significant overlap in their pathophysiological mechanisms. However, research exploring the commonali…

peer-review 2024
Author response for "Emerging Bioengineering Breakthroughs in Precision Diagnosis and Therapy for Endometriosis and Adenomyosis"
·doi:10.1039/d4tb01755b/v2/response1
review 2024
Emerging bioengineering breakthroughs in precision diagnosis and therapy for endometriosis and adenomyosis
Journal of materials chemistry. B ·doi:10.1039/d4tb01755b

Endometriosis and adenomyosis are debilitating gynecological conditions that severely affect the quality of life of women. Traditional diagnostic and treatment methods, including laparoscopic surgery and hormonal therapy, face significant l…

article 2024
Treatment of endometriosis with mifepristone mediated by nanostructured lipid carriers
Drug delivery and translational research ·doi:10.1007/s13346-024-01661-3

Mifepristone, a progesterone receptor antagonist, was initially used to terminate early pregnancy. As scientific research advanced, it emerged to be effective in the treatment of various tumors and tumor-like conditions such as endometriosi…

article 2022
Hyaluronic Acid-Modified Nanoplatforms as a Vector for Targeted Delivery of Autophagy-Related Gene to the Endometriotic Lesions in Mice
Frontiers in bioengineering and biotechnology ·doi:10.3389/fbioe.2022.918368

This investigation probed endometriosis treatment using targeted nanoparticles (NPs) to modulate autophagic activity. To that end, a novel form of polymer-based NP gene delivery platform consisting of polyethyleneimine (PEI) conjugated to s…

2019
Co-Delivery of Curcumin and Paclitaxel by "Core-Shell" Targeting Amphiphilic Copolymer to Reverse Resistance in the Treatment of Ovarian Cancer.
International journal of nanomedicine ·doi:10.2147/ijn.s224579

BackgroundOvarian cancer is a common malignancy in the female reproductive system with a high mortality rate. The most important reason is multidrug resistance (MDR) of cancer chemotherapy. To reduce side effects, reverse resistance and imp…