Dina R

ORCID: 0000-0001-7673-1801 · 2 papers in corpus

2010

Definition of microRNAs that repress expression of the tumor suppressor gene FOXO1 in endometrial cancer.

Cancer research ·doi:10.1158/0008-5472.can-09-1891

Endometrial cancer is the most common malignancy of the lower female reproductive tract. The tumor suppressor FOXO1 is downregulated in endometrial cancer compared with normal endometrium but the underlying mechanisms are not well understoo…

article 2010

Novel Hydroxysteroid (17β) Dehydrogenase 1 Inhibitors Reverse Estrogen-Induced Endometrial Hyperplasia in Transgenic Mice

The American Journal of Pathology ·doi:10.2353/ajpath.2010.090325

Local estrogen production plays a key role in proliferative endometrial disorders, such as endometrial hyperplasia and cancer. Hydroxysteroid (17beta) dehydrogenase 1 (HSD17B1) is an enzyme that catalyzes with high efficiency the conversion…