Zihao Zhao

ORCID: 0009-0009-5322-9451 · 1 paper in corpus

2025

High-resolution spatial analysis reveals pregnenolone metabolism as a potential target for immuno-suppressive microenvironment of BRAF mutant colorectal cancer

·doi:10.1101/2025.09.01.673435

BRAF mutant colorectal cancer (CRC) is highly aggressive and often resistant to traditional therapies, presenting a significant challenge in cancer immunotherapy. Understanding the tumor microenvironment (TME) and identifying novel immune c…