Massimiliano Cocca

No ORCID on file · 4 papers in corpus · active 2015-2023

Study types

  • other 1

Condition tags

  • endometriosis 1
other 2023
Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus
Nature human behaviour ·doi:10.1038/s41562-023-01528-6

Identifying genetic determinants of reproductive success may highlight mechanisms underlying fertility and identify alleles under present-day selection. Using data in 785,604 individuals of European ancestry, we identified 43 genomic loci a…

2019
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Nature genetics ·doi:10.1038/s41588-019-0447-2

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

2018
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Nature genetics ·doi:10.1038/s41588-017-0011-x

Genome-wide association studies (GWAS) have identified >250 loci for body mass index (BMI), implicating pathways related to neuronal biology. Most GWAS loci represent clusters of common, noncoding variants from which pinpointing causal gene…

2015
Purging of deleterious variants due to drift and founder effect in Italian populations with extended autozygosity
·doi:10.1101/022947

Purging through inbreeding occurs when consanguineous marriages increases the rate at which deleterious alleles are present in a homozygous state. In this study we carried out low-read depth (4-10x) whole-genome sequencing in 568 individual…