Nawrocki MJ

ORCID: 0000-0003-3753-755X · 4 papers in corpus
2021
Human Granulosa Cells-Stemness Properties, Molecular Cross-Talk and Follicular Angiogenesis.
Cells ·doi:10.3390/cells10061396

The ovarian follicle is the basic functional unit of the ovary, comprising theca cells and granulosa cells (GCs). Two different types of GCs, mural GCs and cumulus cells (CCs), serve different functions during folliculogenesis. Mural GCs pr…

2019
Genes responsible for proliferation, differentiation, and junction adhesion are significantly up-regulated in human ovarian granulosa cells during a long-term primary in vitro culture.
Histochemistry and cell biology ·doi:10.1007/s00418-018-1750-1

The human ovarian granulosa cells (GCs) surround the oocyte and form the proper architecture of the ovarian follicle. The ability of GCs to proliferate and differentiate in the conditions of in vitro culture has been proven. However, there …

2019
'Heart development and morphogenesis' is a novel pathway for human ovarian granulosa cell differentiation during long‑term in vitro cultivation‑a microarray approach.
Molecular medicine reports ·doi:10.3892/mmr.2019.9837

Granulosa cells (GCs) have many functions in the endocrine system. Most notably, they produce progesterone following ovulation. However, it has recently been proven that GCs can change their properties when subjected to long‑term culture. I…

2017
Expression Profile of Genes Regulating Steroid Biosynthesis and Metabolism in Human Ovarian Granulosa Cells-A Primary Culture Approach.
International journal of molecular sciences ·doi:10.3390/ijms18122673

Because of the deep involvement of granulosa cells in the processes surrounding the cycles of menstruation and reproduction, there is a great need for a deeper understanding of the ways in which they function during the various stages of th…