Christine N. Metz

ORCID: 0000-0002-1467-4466 · 64 papers in corpus
2008
Induction of cyclooxygenase-2 expression and prostaglandin E2 secretion by macrophage migration inhibitory factor in ectopic endometrial cells: role in the pathophysiology of endometriosis
·doi:10.1016/j.fertnstert.2008.07.943
lab-animal 2008
Involvement of nuclear factor-kappaB in macrophage migration inhibitory factor gene transcription up-regulation induced by interleukin- 1 beta in ectopic endometrial cells
Fertility and sterility ·doi:10.1016/j.fertnstert.2008.05.017

OBJECTIVE: To investigate the involvement of the nuclear factor (NF)-kappaB in the interleukin (IL)-1 beta-mediated macrophage migration inhibitory factor (MIF) gene activation. DESIGN: Prospective study. SETTING: Human reproduction resea…

2008
Macrophage migration inhibitory factor (MIF)-induced signaling pathways in human endometrial stromal cells of women with and without endometriosis
·doi:10.1016/j.fertnstert.2008.07.249
other 2007
Direct effect of macrophage migration inhibitory factor on sperm function: possible involvement in endometriosis-associated infertility
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.04.002

OBJECTIVE: To evaluate the effect of macrophage migration inhibitory factor (MIF) on sperm capacitation, a maturational process that occurs in the female reproductive tract and enables spermatozoa to become fully competent at fertilizing th…

observational 2006
Macrophage migration inhibitory factor expression in the intrauterine endometrium of women with endometriosis varies with disease stage, infertility status, and pelvic pain
Fertility and sterility ·doi:10.1016/j.fertnstert.2005.10.073

OBJECTIVE: To evaluate the concentrations of macrophage migration inhibitory factor (MIF) in the eutopic endometrial tissue of women with and without endometriosis. DESIGN: Retrospective study using ELISA to measure MIF concentrations in t…

2005
Development of an Experimental Infertility Model: Involvement of Macrophage Migration Inhibitory Factor (MIF) on Embryonic Implantation
·doi:10.1016/j.fertnstert.2005.07.1165
observational 2005
Elevated levels of macrophage migration inhibitory factor in the peripheral blood of women with endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2004.10.039

OBJECTIVE: To evaluate the concentrations of macrophage migration inhibitory factor (MIF) in the peripheral blood of normal women and patients with endometriosis. DESIGN: Retrospective study using ELISA to measure peripheral blood MIF. SE…

2005
Macrophage Migration Inhibitory Factor Induces Matrix Metalloproteinase-2 and -9 Secretion, Synthesis and Activation in Ectopic and Eutopic Endometrial Cells of Women With Endometriosis
·doi:10.1016/j.fertnstert.2005.07.468
2005
Macrophage Migration Inhibitory Factor Up-Regulates Cyclooxygenase-2 Expression in Endometrial Cells
·doi:10.1016/j.fertnstert.2005.07.484
2005
Marked Expression of Macrophage Migration Inhibitory Factor in the Intrauterine Endometrium of Women With Endometriosis Varying With the Disease Stage, the Infertility Status and Pelvic Pain
·doi:10.1016/j.fertnstert.2005.07.301
lab-animal 2005
Stimulation of macrophage migration inhibitory factor expression in endometrial stromal cells by interleukin 1, beta involving the nuclear transcription factor NFkappaB
Biology of reproduction ·doi:10.1095/biolreprod.104.038331

Endometriosis, the ectopic development of endometrial tissue, is, particularly in peritoneal endometriosis, believed to result from tubal reflux of menstrual tissue. The release of cytokines and growth factors by refluxed endometrial cells …

2002
Macrophage migration inhibitory factor expression in the human endometrium is cycle phase-dependent and markedly increased in women having endometriosis
·doi:10.1016/s0015-0282(02)04064-5
other 2002
Macrophage migration inhibitory factor is markedly expressed in active and early-stage endometriotic lesions
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.87.2.8260

The establishment of a new vascular supply is essential for the survival of endometrial tissue and its development in ectopic locations. We have previously shown that ectopic endometrial cells release an important mitogenic activity for hum…

other 2002
Marked elevation of macrophage migration inhibitory factor in the peritoneal fluid of women with endometriosis
Fertility and sterility ·doi:10.1016/s0015-0282(02)03189-8

OBJECTIVE: To evaluate the presence of macrophage migration inhibitory factor (MIF) in the peritoneal fluid of normal fertile women and patients with endometriosis and its growth-promoting activity toward human endothelial cells. DESIGN: R…