Wabitsch M

No ORCID on file · 3 papers in corpus · active 2019-2026
2026
Inhibition of the androgen-activating enzyme AKR1C3 selectively decreases systemic and intra-adipose 11-oxygenated androgens in women
·doi:10.64898/2026.03.27.714735

Androgen excess drives metabolic and reproductive complications in polycystic ovary syndrome (PCOS), affecting 10-15% of women globally. Aldo-keto reductase 1C3 (AKR1C3) converts inactive precursors from both the classic and the recently id…

2025
Youths with Extreme Obesity: A High-Risk Group for Pain and Mental Health Impairments.
Obesity facts ·doi:10.1159/000540888

IntroductionYouths with extreme obesity (body mass index [BMI] ≥40) are at increased risk for physical and mental health impairments. Nevertheless, this patient group has received little attention in research. This study aimed to analyze th…

2019
Detailed Functional Characterization of a Waist-Hip Ratio Locus in 7p15.2 Defines an Enhancer Controlling Adipocyte Differentiation.
iScience ·doi:10.1016/j.isci.2019.09.006

We combined CAGE sequencing in human adipocytes during differentiation with data from genome-wide association studies to identify an enhancer in the SNX10 locus on chromosome 7, presumably involved in body fat distribution. Using reporter a…