Bakaletz LO

ORCID: 0000-0002-0017-1710 · 2 papers in corpus

2026

Rapid means of biofilm disruption induce the newly released (NRel) phenotype of enhanced antibiotic sensitivity.

Frontiers in microbiology ·doi:10.3389/fmicb.2026.1734540

IntroductionBiofilms are communities of microorganisms encased in a self-produced matrix, a structure that makes resident bacteria up to 1,000 times more resistant to antibiotics than their free-living, or planktonic, counterparts. Intrigui…

2023

Nontypeable Haemophilus influenzae released from biofilm residence by monoclonal antibody directed against a biofilm matrix component display a vulnerable phenotype.

Scientific reports ·doi:10.1038/s41598-023-40284-5

Bacterial biofilms contribute significantly to pathogenesis, recurrence and/or chronicity of the majority of bacterial diseases due to their notable recalcitrance to clearance. Herein, we examined kinetics of the enhanced sensitivity of non…