Akshanth R. Polepally

ORCID: 0000-0002-5938-6062 · 6 papers in corpus · active 2018-2021

Study types

  • article 4
  • other 1
  • review 1

Condition tags

  • endometriosis 6
  • mesh:D004715 5
  • dysmenorrhea 1
  • mesh:D017699 1
article 2021
Clinical and translational science ·doi:10.1111/cts.13040

Abstract Elagolix is a novel, oral gonadotropin‐releasing hormone receptor antagonist indicated for the management of moderate to severe pain associated with endometriosis and heavy menstrual bleeding associated with uterine fibroids. Consi…

article 2020
Journal of clinical pharmacology ·doi:10.1002/jcph.1689

Elagolix is an oral gonadotropin-releasing hormone receptor antagonist indicated for the management of endometriosis-associated pain and in combination with estradiol/norethindrone acetate indicated for the management of heavy menstrual ble…

review 2020
Clinical pharmacokinetics ·doi:10.1007/s40262-019-00840-7

The clinical pharmacology of elagolix was extensively evaluated in clinical studies in healthy subjects and in women with endometriosis. Elagolix pharmacokinetics (PK) show significant population variability, however they are minimally affe…

other 2020
CPT: pharmacometrics & systems pharmacology ·doi:10.1002/psp4.12545

Elagolix is an oral gonadotropin-releasing hormone antagonist approved by the US Food and Drug Administration (FDA) for the management of moderate-to-severe pain associated with endometriosis and in combination with estradiol/norethindrone …

article 2020
CPT: pharmacometrics & systems pharmacology ·doi:10.1002/psp4.12560

Elagolix is a novel oral gonadotropin releasing hormone receptor antagonist, that can suppress estradiol in a dose‐dependent manner. It is indicated for management of moderate‐to‐severe pain associated with endometriosis. A population expos…

article 2018
Clinical pharmacokinetics ·doi:10.1007/s40262-018-0629-6