Dan Liu

ORCID: 0000-0001-6168-9153 · 38 papers in corpus
lab-animal 2022
Autophagy ·doi:10.1080/15548627.2022.2038994

Intrauterine adhesions (IUA), characterized by endometrial fibrosis, is a common cause of uterine infertility. We previously demonstrated that partial epithelial-mesenchymal transition (EMT) and the loss of epithelial homeostasis play a vit…

lab-animal 2022
·doi:10.21203/rs.3.rs-1539861/v1

Abstract Background: Adenomyosis is a benign gynecological disorder but has detrimental effect on female fertility of childbearing age. Melatonin is a classic antioxidant and free radical scavenger to protect against tissue damage, and exer…

lab-animal 2022
Annals of translational medicine ·doi:10.21037/atm-22-5493

BACKGROUND: Adenomyosis is a common gynecological disease which seriously impacts female fertility and is increasing in incidence in women of childbearing age. Melatonin has beneficial effects on reproductive processes. However, its impact …

observational 2022
Frontiers in endocrinology ·doi:10.3389/fendo.2022.1038184

BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting reproductive age females and an important cause of infertility. Although the etiology is complex and its pathogenesis remains unclear, the patholog…

other 2021
PloS one ·doi:10.1371/journal.pone.0250685

BACKGROUND: Chinese herbal footbaths are an external therapy of traditional Chinese medicine that has been widely used to treat dysmenorrhea. This review aims to systematically evaluate its efficacy and safety for the treatment of dysmenorr…

other 2021
Aging ·doi:10.18632/aging.203710

Although endometrioid carcinoma (EC) and endometrioid ovarian carcinoma (EnOC) display similar pathological features, their molecular characteristics remain to be determined. Somatic mutation data from 2777 EC, 423 EnOC, and 57 endometriosi…

lab-animal 2021
Pathology oncology research : POR ·doi:10.3389/pore.2021.1609761

Intrauterine adhesion (IUA) is one of the most prevalent reproductive system diseases in females. MicroRNAs (miRNAs) are reported to be master regulators in a variety of diseases, including IUA, but the role of microRNA-543 (miR-543) in IUA…

lab-animal 2020
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas ·doi:10.1590/1414-431x20209794

Although estrogen has crucial functions for endometrium growth, the specific dose and underlying molecular mechanism in intrauterine adhesion (IUA) remain unclear. In this study, we aimed to investigate the effects of estrogen on epithelial…

observational 2019
Medicine ·doi:10.1097/md.0000000000015512

At present, the precise role of human menopausal gonadotropin (HMG) and recombinant luteinizing hormone (rLH) supplementation at an early time of follicular phase on in vitro fertilization (IVF)/intra cytoplasmatic sperm injection (ICSI) ou…

other 2019
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.13191

PROBLEM: Asherman's syndrome (AS) is characterized by endometrial fibrosis leading to intrauterine adhesions and symptoms like hypomenorrhea, infertility, and recurrent pregnancy loss. Macrophages are key regulators of inflammation, tissue …

lab-animal 2018
Nature communications ·doi:10.1038/s41467-018-03590-5

Chemoresistance is a major unmet clinical obstacle in ovarian cancer treatment. Epigenetics plays a pivotal role in regulating the malignant phenotype, and has the potential in developing therapeutically valuable targets that improve the di…

observational 2018
Journal of vascular research ·doi:10.1159/000488392

BACKGROUND/AIMS: This study describes the peritoneal microcirculation, compares quantitative parameters and angioarchitecture to the standard of sublingual microcirculatory assessment, and determines the practical feasibility of this method…

lab-animal 2017
Scientific reports ·doi:10.1038/s41598-017-00517-w

Survivin is a proto-oncogene biomarker known for its anti-apoptotic and cell cycle regulating properties induced by the activation of the phosphoinositide 3-kinase (PI3K)/Akt pathway. In the context of non-cancer pathology, such as rheumato…