Charlotte H Clarke

No ORCID on file · 1 paper in corpus

diagnostic-accuracy 2011

Proteomic biomarkers apolipoprotein A1, truncated transthyretin and connective tissue activating protein III enhance the sensitivity of CA125 for detecting early stage epithelial ovarian cancer

Gynecologic Oncology ·doi:10.1016/j.ygyno.2011.06.002

OBJECTIVE: The low prevalence of ovarian cancer demands both high sensitivity (>75%) and specificity (99.6%) to achieve a positive predictive value of 10% for successful early detection. Utilizing a two stage strategy where serum marker(s) …