Yan GJ

No ORCID on file · 2 papers in corpus

2024

Embryo-Derived Cathepsin B Promotes Implantation and Decidualization by Activating Pyroptosis.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) ·doi:10.1002/advs.202402299

Embryo implantation and decidualization are crucial for a successful pregnancy. How the inflammatory response is regulated during these processes is undefined. Pyroptosis is an inflammatory form of cell death mediated by gasdermin D (GSDMD)…

other 2013

PCAF impairs endometrial receptivity and embryo implantation by down-regulating β3-integrin expression via HOXA10 acetylation

The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2013-1429

BACKGROUND: Homeobox A10 (HOXA10), a key transcription factor, plays a critical role in endometrial receptivity by regulating the expression of downstream target genes, such as β3-integrin (ITGB3), but little is understood about the mechani…