Marcus Koppitz

ORCID: 0000-0003-3943-9291 · 2 papers in corpus · active 2019

Study types

  • article 1
  • other 1

Condition tags

  • endometriosis 2
  • mesh:D004715 1
article 2019
Discovery and optimization of pyridyl-cycloalkyl-carboxylic acids as inhibitors of microsomal prostaglandin E synthase-1 for the treatment of endometriosis
Bioorganic & medicinal chemistry letters ·doi:10.1016/j.bmcl.2019.07.007
other 2019
Discovery of BAY-298 and BAY-899: Tetrahydro-1,6-naphthyridine-Based, Potent, and Selective Antagonists of the Luteinizing Hormone Receptor Which Reduce Sex Hormone Levels in Vivo
Journal of medicinal chemistry ·doi:10.1021/acs.jmedchem.9b01382

The human luteinizing hormone receptor (hLH-R) is a member of the glycoprotein hormone family of G-protein-coupled receptors (GPCRs), activated by luteinizing hormone (hLH) and essentially involved in the regulation of sex hormone productio…