Shi JW

No ORCID on file · 9 papers in corpus · active 2019-2025

Study types

  • article 2
  • review 1

Condition tags

  • endometriosis 3
  • infertility 1
2025
Decidual stromal cells drive CD16+ macrophages towards an immunoregulatory phenotype via extracellular matrix-adhesion molecule interaction during early pregnancy.
Frontiers in immunology ·doi:10.3389/fimmu.2025.1747323

IntroductionDramatic alterations of the extracellular matrix (ECM), which can regulate cell behavior by binding to adhesion molecules and are intrinsically linked to immune regulation, occur in decidualization during early pregnancy. Decidu…

2023
Epididymis cell atlas in a patient with a sex development disorder and a novel NR5A1 gene mutation.
Asian journal of andrology ·doi:10.4103/aja202226

This study aims to characterize the cell atlas of the epididymis derived from a 46,XY disorders of sex development (DSD) patient with a novel heterozygous mutation of the nuclear receptor subfamily 5 group A member 1 (NR5A1) gene. Next-gene…

2023
Identification of potential biomarkers and immune infiltration characteristics in recurrent implantation failure using bioinformatics analysis.
Frontiers in immunology ·doi:10.3389/fimmu.2023.992765

IntroductionRecurrent implantation failure (RIF) is a frustrating challenge because the cause is unknown. The current study aims to identify differentially expressed genes (DEGs) in the endometrium on the basis of immune cell infiltration c…

2022
An IGF1-expressing endometrial stromal cell population is associated with human decidualization.
BMC biology ·doi:10.1186/s12915-022-01483-0

BackgroundDecidualization refers to the process of transformation of endometrial stromal fibroblast cells into specialized decidual stromal cells that provide a nutritive and immunoprivileged matrix essential for blastocyst implantation and…

2022
Excess Heme Promotes the Migration and Infiltration of Macrophages in Endometrial Hyperplasia Complicated with Abnormal Uterine Bleeding.
Biomolecules ·doi:10.3390/biom12060849

In patients, endometrial hyperplasia (EH) is often accompanied by abnormal uterine bleeding (AUB), which is prone to release large amounts of heme. However, the role of excess heme in the migration and infiltration of immune cells in EH com…

2022
Single-cell transcriptome profiling of the human endometrium of patients with recurrent implantation failure.
Theranostics ·doi:10.7150/thno.74053

Introduction: Despite great advances in assisted reproductive technology (ART), recurrent implantation failure (RIF) cannot be effectively avoided. Notably, cellular characteristics and communication that regulate endometrial receptivity an…

review 2021
Ovarian hormones-autophagy-immunity axis in menstruation and endometriosis
Theranostics ·doi:10.7150/thno.55241

Menstruation occurs in few species and involves a cyclic process of proliferation, breakdown and regeneration under the control of ovarian hormones. Knowledge of normal endometrial physiology, as it pertains to the regulation of menstruatio…

article 2021
Protopanaxadiol improves endometriosis associated infertility and miscarriage in sex hormones receptors-dependent and independent manners
International journal of biological sciences ·doi:10.7150/ijbs.58657

Background: Patients with endometriosis (EMs) have high risks of infertility and spontaneous abortion. How to remodel the fertility of patients with EMs has always been the hot spot and difficulty in the field of reproductive medicine. As a…

article 2019
IL-2 and IL-27 synergistically promote growth and invasion of endometriotic stromal cells by maintaining the balance of IFN-γ and IL-10 in endometriosis
Reproduction (Cambridge, England) ·doi:10.1530/rep-19-0411

Immune cells and cytokines have important roles in the pathogenesis of endometriosis. However, the production and role of cytokines of T helper type 1 (Th1) and Th2 cells in the progress of endometriosis have remained to be fully elucidated…