Hoffmeister M

ORCID: 0000-0002-8307-3197 · 2 papers in corpus

2019

Discovery of common and rare genetic risk variants for colorectal cancer.

Nature genetics ·doi:10.1038/s41588-018-0286-6

To further dissect the genetic architecture of colorectal cancer (CRC), we performed whole-genome sequencing of 1,439 cases and 720 controls, imputed discovered sequence variants and Haplotype Reference Consortium panel variants into genome…

2014

Estimating the heritability of colorectal cancer.

Human molecular genetics ·doi:10.1093/hmg/ddu087

A sizable fraction of colorectal cancer (CRC) is expected to be explained by heritable factors, with heritability estimates ranging from 12 to 35% twin and family studies. Genome-wide association studies (GWAS) have successfully identified …