Fang P

ORCID: 0000-0001-5305-2830 · 4 papers in corpus
2026
Inhibition of ERK5 activity ameliorates osteoarthritis by suppressing NLRP3 inflammasome-mediated chondrocyte pyroptosis.
Bone research ·doi:10.1038/s41413-026-00573-x

Osteoarthritis (OA) is a widespread degenerative joint disorder manifesting as chronic pain, functional impairment, and progressive disability, imposing a substantial burden on global public health. Despite extensive research, the precise m…

2023
OBHS Drives Abnormal Glycometabolis Reprogramming via GLUT1 in Breast Cancer.
International journal of molecular sciences ·doi:10.3390/ijms24087136

Due to the poor metabolic conditions fomenting the emergence of the Warburg effect (WE) phenotype, abnormal glycometabolism has become a unique and fundamental research topic in the field of tumor biology. Moreover, hyperglycemia and hyperi…

other 2020
Three-dimensional oxabicycloheptene sulfonate targets the homologous recombination and repair programmes through estrogen receptor α antagonism
Cancer letters ·doi:10.1016/j.canlet.2019.10.019

Selective estrogen receptor modulators (SERMs) are a class of structurally diverse compounds, which have been extensively used to treat hormone-responsive cancers due to their unique partially agonistic and antagonistic properties toward es…

article 2012
Effect of mifepristone on COX-2 both in eutopic and ectopic endometrium in mouse endometriotic model
Archives of gynecology and obstetrics ·doi:10.1007/s00404-012-2379-2

ObjectiveTo study the influence of mifepristone on the expression of cyclooxygenase 2 (COX-2) protein and COX-2 mRNA and then to evaluate the mechanism.MethodsAfter the establishment of 30 mice endometriosis models, the mice were randomly d…