Fan L

ORCID: 0000-0001-6021-9520 · 55 papers in corpus
other 2019
Aging ·doi:10.18632/aging.102589

Genetic causes of male infertility that is associated with aging are largely unknown. This study was designed to identify novel pathogenic variants of FOXP3 gene causing azoospermia. One homozygous (c.155 G > T) pathogenic variant of FOXP3 …

other 2018
Scientific reports ·doi:10.1038/s41598-018-25032-4

Semen analysis is used for diagnosing male infertility and evaluating male fertility for more than a century. However, the semen analysis simply represents the population characteristics of sperm. It is not a comprehensive assessment of the…

meta-analysis 2018
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-018-0398-y

OBJECTIVE: To determine whether acrosome function scoring-including acrosomal enzyme (AE) levels and acrosome reaction (AR) results-can predict fertilization rate in vitro. METHODS: We examined the predictive value of acrosomal enzymes (AE…

observational 2012
Cancer biomarkers : section A of Disease markers ·doi:10.3233/cbm-130304

BACKGROUND: Carbohydrate antigen 125 (CA-125) is a glycoprotein produced by epithelial and mesothelial cells. Serum CA-125 can be elevated in many benign and malignant conditions in which these tissues are involved. METHODS: We measured se…

lab-animal 2007
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.01.044

OBJECTIVE: To determine the role of interleukin-1 receptor type II (IL-1RII) in the pathogenesis of endometriosis. DESIGN: Cultures of endometrial cells exposed to soluble IL-1RII or the recombinant adenovirus of IL-1RII (rAd-RII). SETTIN…