Walker C

Adenomyosis is a gynecologic condition characterized by ectopic endometrial tissue within the uterine myometrium. First described in 1860 by the German pathologist Carl von Rokitansky, the histopathologic finding was termed “cystosarcoma ad…

OBJECTIVE: To evaluate the impact and diagnostic accuracy of an endometriosis-specific magnetic resonance imaging (MRI) protocol on the management of deep endometriosis (DIE). STUDY DESIGN: Retrospective cohort study at the Cleveland Clini…

Abstract Women have reported both menstrual disruption following SARS-CoV-2 infection and that long COVID symptoms change across the menstrual cycle. Yet there is a lack of female-specific research on COVID and menstruation. We aimed to de…

Women have reported menstrual changes following SARS-CoV-2 infection and variation in long COVID symptoms across the menstrual cycle. We examined (i) whether COVID is linked to abnormal uterine bleeding (AUB), (ii) if long COVID symptoms va…

BackgroundA clinical dashboard is a data-driven clinical decision support tool visualizing multiple key performance indicators in a single report while minimizing time and effort for data gathering. Studies have shown that including patient…

CONTEXT: Heavy menstrual bleeding (HMB) is common and debilitating, but the precise endometrial mechanisms causing increased menstrual blood loss (MBL) remain undefined. We have previously identified a role for hypoxia in endometrial repair…

STUDY QUESTION: Can markers of human endometrial hypoxia be detected at menstruation in vivo? SUMMARY ANSWER: Our in vivo data support the presence of hypoxia in menstrual endometrium of women during physiological menstruation. WHAT IS KNOW…

Heavy menstrual bleeding is common and debilitating but the causes remain ill defined. Rates of obesity in women are increasing and its impact on menstrual blood loss (MBL) is unknown. Therefore, we quantified BMI and MBL in women not takin…

Background/aimsThe objective of this study was to assess in vivo gene therapy of uterine leiomyomas in the Eker rat model using adenovirus (Ad)-mediated delivery of herpes simplex virus 1 thymidine kinase gene (HSV1TK) followed by ganciclov…

OBJECTIVE: To evaluate the possible role of endocrine-disrupting compounds (EDCs) on female reproductive disorders emphasizing developmental plasticity and the complexity of endocrine-dependent ontogeny of reproductive organs. Declining con…