Fernando Luiz Affonso Fonseca

observational 2024

Low and High-Normal FMR1 Triplet Cytosine, Guanine Guanine Repeats Affect Ovarian Reserve and Fertility in Women Who Underwent In Vitro Fertilization Treatment? Results from a Cross-Sectional Study

DNA and cell biology ·doi:10.1089/dna.2023.0395

Dynamic mutations in the 5' untranslated region of FMR1 are associated with infertility. Premutation alleles interfere with prenatal development and increase infertility risks. The number of CGG repeats that causes the highest decrease in o…

diagnostic-accuracy 2020

BIRC5/Survivin Expression as a Non-Invasive Biomarker of Endometriosis

Diagnostics ·doi:10.3390/diagnostics10080533

The etiology of endometriosis is highly complex, and although it is a benign disease, it has several biological behaviors similar to malignant lesions, including cell invasion, neo-angiogenesis, and decreased apoptosis. Survivin is a protei…

nonrandomized-trial 2014

Analysis of FokI polymorphism of vitamin D receptor gene in intervertebral disc degeneration

Genetic testing and molecular biomarkers ·doi:10.1089/gtmb.2014.0030

AIM: We have hypothesized a possible relationship between disc degeneration (DD) and VDR FokI/T2C polymorphism. METHODS: A case-control study was performed comprising 121 Brazilian patients with confirmed DD by nuclear magnetic resonance a…