Zishui Fang — Endo Lab

nonrandomized-trial 2026

Phase 1 dose-escalation trial of sub-endometrial injection of human embryonic stem cells-derived immunity-and-matrix-regulatory cells to promote endometrial angiogenesis in refractory intrauterine adhesion

Molecular therapy : the journal of the American Society of Gene Therapy ·doi:10.1016/j.ymthe.2025.09.035

Clinical application of mesenchymal stem cells for endometrial repair has been hampered by variability in cell quality, large-scale production, and uncertainty regarding the optimal delivery route. In this study, we investigated the therape…

observational 2025

Enhancing understanding of endometrial function in patients with PCOS: clinical and immunological insights

Journal of ovarian research ·doi:10.1186/s13048-025-01638-x

OBJECTIVE: To evaluate the pregnancy and perinatal outcomes of different phenotypes of polycystic ovary syndrome (PCOS) patients during the frozen embryo transfer (FET) cycles. Additionally, to analyze the T cell balance in the endometrium …

observational 2023

Which endometrial preparation protocol provides better pregnancy and perinatal outcomes for endometriosis patients in frozen-thawed embryo transfer cycles? A retrospective study on 1413 patients

Journal of ovarian research ·doi:10.1186/s13048-023-01095-4

OBJECTIVE: To determine the optimal endometrial preparation protocol for a frozen embryo transfer in patients with endometriosis. DESIGN: Retrospective cohort study. SETTING: Tertiary care academic medical center. PATIENT(S): One thousan…

observational 2020

Performing ICSI within 4 hours after denudation optimizes clinical outcomes in ICSI cycles

Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-020-00587-y

BACKGROUND: The study aimed to investigate whether and how general and partial time intervals between processes, from human chorionic gonadotrophin (HCG) trigger to intracytoplasmic sperm injection (ICSI), affected the laboratory and reprod…

2005

Defect of Stroma-Epithelial Interaction in Endometriosis is Responsible for Lack of Induction of 17β-Hydroxsteroid Dehydrogenase Type 2 by Progesterone

·doi:10.1016/j.fertnstert.2005.07.469

2001

Regulation of aromatase P450 promoter (II) activity in endometriotic stromal cells by CCAAT/enhancer binding proteins (C/EBPs).

·doi:10.1016/s0015-0282(01)02149-5

2001

Transcriptional regulation of the CYP1A1 gene by dioxin in eutopic endometrial and endometriotic stromal cells.

·doi:10.1016/s0015-0282(01)02156-2

2001

Treatment with the aromatase inhibitor letrozole significantly reduced the size of ectopic uterine implants.

·doi:10.1016/s0015-0282(01)02153-7

2000

Use of Transgenic Knockout Mice to Understand the Roles of Estrogen and Progesterone in the Growth of Ectopic Uterine Tissue as a Model for Endometriosis

·doi:10.1016/s0015-0282(00)01564-8