Yee D

No ORCID on file · 2 papers in corpus · active 2015-2025
2025
A roadmap to reduce the incidence and mortality of breast cancer by rethinking our approach to women's health.
Breast cancer research and treatment ·doi:10.1007/s10549-024-07522-4

Despite progress, breast cancer remains the most feared disease among women. In the USA alone, the incidence is now almost 300,000 new cancers per year, a rate that has nearly doubled in the last 30 years. Most women survive, but over 40,00…

2015
Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling.
Nature communications ·doi:10.1038/ncomms7118

Ovarian clear-cell carcinoma (OCCC) is an aggressive form of ovarian cancer with high ARID1A mutation rates. Here we present a mutant mouse model of OCCC. We find that ARID1A inactivation is not sufficient for tumour formation, but requires…