Leah Prentice

ORCID: 0000-0001-8011-2835 · 6 papers in corpus · active 2010-2018

Study types

  • article 6

Condition tags

  • endometriosis 6
  • mesh:D004715 4
  • infertility 1
  • die_deep_infiltrating 1
article 2018
Human Reproduction ·doi:10.1093/humrep/dey332

STUDY QUESTION: Does incisional endometriosis (IE) harbor somatic cancer-driver mutations? SUMMARY ANSWER: We found that approximately one-quarter of IE cases harbor somatic-cancer mutations, which commonly affect components of the MAPK/RAS…

article 2015
·doi:10.1158/1557-3265.ovcasymp14-as18

Abstract Introduction: Clear Cell ovarian carcinomas (CCC) represent 10% of ovarian carcinomas, with outcomes for high-stage significantly worse than high-grade serous form. The complete mutational landscape, the molecular basis of the tran…

article 2015
The Journal of Pathology ·doi:10.1002/path.4516

Endometriosis is a significant risk factor for clear cell and endometrioid ovarian cancers and is often found contiguous with these cancers. Using whole-genome shotgun sequencing of seven clear cell ovarian carcinomas (CCC) and targeted seq…

article 2014
·doi:10.1158/1538-7445.am2014-lb-312

Abstract Clear Cell ovarian carcinomas (CCC) represent ∼10% of ovarian carcinomas, with outcomes for high-stage cases significantly worse than the more common high-grade serous form. Response to standard chemotherapies are poor and efforts …

article 2013
Human Reproduction ·doi:10.1093/humrep/det050

STUDY QUESTION: Is there a global consensus on the management of endometriosis that considers the views of women with endometriosis? SUMMARY ANSWER: It was possible to produce an international consensus statement on the current management o…

article 2010
The New England journal of medicine ·doi:10.1056/nejmoa1008433

BACKGROUND: Ovarian clear-cell and endometrioid carcinomas may arise from endometriosis, but the molecular events involved in this transformation have not been described. METHODS: We sequenced the whole transcriptomes of 18 ovarian clear-ce…