Boxian Huang

ORCID: 0000-0001-9913-9077 · 3 papers in corpus
2026
FTO Controls Endometrial Receptivity and Embryo Implantation through Regulating m6A and H3K27me3.
Communications biology ·doi:10.1038/s42003-026-10247-3

Endometrial receptivity is essential for implantation and pregnancy, yet the role of the m6A demethylase FTO remains unclear. We examined epithelial Fto and Wnt signaling during the implantation window using CRISPR/Cas9 Fto knockout mice an…

2025
Mettl3/Eed/Ythdc1 regulatory axis controls endometrial receptivity and function.
Communications biology ·doi:10.1038/s42003-025-07667-y

The regulatory mechanism between N6-methyladenosine (m6A) RNA methylation and histone modification in endometrial receptivity remains poorly understood. In this study, we depict that RIF induced m6A and Mettl3 level restrain, affecting H3K2…

2025
The N6-methyladenosine landscape of ovarian development and aging highlights the regulation by RNA stability and chromatin state.
Aging cell ·doi:10.1111/acel.14376

The versatile epigenetic modification known as N6-methyladenosine (m6A) has been demonstrated to be pivotal in numerous physiological and pathological contexts. Nonetheless, the precise regulatory mechanisms linking m6A to histone modificat…