Endometriosis (EMS) is a complex gynecological disorder whose pathogenesis remains poorly understood, with lipid metabolism, immune regulation, and inflammation likely playing pivotal roles. This Mendelian randomization study investigates c…
Recent advances in understanding the modulatory functions of gut and gut microbiota on human diseases facilitated our focused attention on the contribution of the gut to the pathophysiological alterations of many extraintestinal organs, inc…
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Genome-wide association studies (GWAS) have identified >250 loci for body mass index (BMI), implicating pathways related to neuronal biology. Most GWAS loci represent clusters of common, noncoding variants from which pinpointing causal gene…
In the published version of this paper, the name of author Emanuele Di Angelantonio was misspelled. This error has now been corrected in the HTML and PDF versions of the article.
IMPORTANCE: The causal direction and magnitude of the association between telomere length and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility of observational studies to confounding and reverse causa…
AIMS: To study the changes of the metabolic profile during the pathogenesis in monocrotaline (MCT) induced pulmonary arterial hypertension (PAH). METHODS: Forty male Sprague-Dawley (SD) rats were randomly divided into 5 groups (n = 8, each…