Liu Y

OBJECTIVE: To evaluate the effects of a three-stage treatment strategy featured by cold-knife adenomyomectomy, enhanced endometrial protection and postoperative uterine monitoring for severe diffuse adenomyosis on IVF/ICSI and perinatal out…

ObjectiveTo evaluate whether vitamin D supplementation improves live birth rates in women with polycystic ovary syndrome undergoing in vitro fertilisation.DesignMulticentre, double blind, placebo controlled, randomised clinical trial.Settin…

BackgroundTraditional research on the female reproductive tract (FRT) microbiome has focused on the dominance of bacteria, particularly Lactobacillus, as a marker of health. This bacteriocentric paradigm, however, cannot fully explain clini…

BackgroundImmature teratoma is a malignant tumor and accounts for 1%-3% of ovary teratoma. The objective of this study was to find the potential single nucleotide polymorphisms (SNPs), copy number variations (CNVs) and drug targets in the i…

BackgroundHepatocellular carcinoma (HCC) mainly develops in cases of fibrosis and cirrhosis and is accompanied by intestinal flora disorder. HCC also affects CD8+ T cell immune function. 5,7-Dimethoxyflavone (DMF), an active flavonoid with …

Introduction Uterine rupture (UR) during pregnancy refers to a disruption of the uterine wall involving the myometrium and serosa that occurs in association with pregnancy. The global incidence of UR is rising, and this condition can lead t…

Dichloroacetate (DCA), as a pan-inhibitor of pyruvate dehydrogenase kinase, plays a crucial role in energy metabolism and mitochondrial function. DCA decreases lactic acid synthesis, enhances mitochondrial oxidative phosphorylation, and reg…

PurposeThe application of narrow-band imaging for missed early miscarriage treatment remains unclear. This study determined the application advantages of NBI combined with hysteroscopic 7Fr cold knife embryo removal for treating missed earl…

BackgroundThis study aims to investigate the efficacy and safety of dexmedetomidine in treating postoperative acute pain through a clinical randomized controlled trial.MethodsThis study selected 165 patients who underwent general anesthesia…

IntroductionThe burden of gynaecological diseases is increasing globally, affecting women's health, quality of life and fertility. Improving the quality of gynaecological care will enhance patient recovery and improve outcomes of gynaecolog…

BackgroundWhile metabolic syndrome and obesity are established risk factors for infertility, previous studies have neglected age-specific analyses and nonlinear associations, particularly in women aged 20-45 years, a critical demographic fo…

BackgroundOrganochlorine pesticides (OCPs) are extensively dispersed throughout the environment, which potentially have harmful impacts on the female reproductive system. Therefore, the purpose of this study was to clarify the association b…

ObjectivesThis meta-analysis seeks to clarify the relationship between hysterectomy, oophorectomy, and the subsequent risk of developing breast cancer.MethodsA comprehensive literature search was conducted across PubMed, the Cochrane Librar…

Ovarian cancer (OC), one of the most common gynecological cancers, is usually diagnosed at an advanced stage. High-grade serous ovarian cancer (HGSOC) is a histological subtype of OC that accounts for approximately 70% of all OC cases. erb-…

BackgroundElagolix is an oral small molecule second-generation nonpeptide gonadotropin-releasing hormone (GnRH) antagonist drug that can quickly and reversibly inhibit female gonadotropins and ovarian sex hormones. Previous randomized contr…

BackgroundThe atypical hemolytic uremic syndrome (aHUS) presents diagnostic and therapeutic challenges due to overlapping features with other conditions like Preeclampsia/HELLP syndrome and thrombotic thrombocytopenic purpura (TTP). Pregnan…

BackgroundIn clinical practice, scheduling oocyte retrieval is a challenging issue that requires comprehensive consideration of factors such as the woman's age, ovarian response, hormone levels and other variables. Moreover, there is curren…

Myocardial infarction (MI) is one of the most serious cardiovascular diseases in the world. Nevertheless, the majority of diagnostic procedures conducted subsequent to the illness do not provide any means to prevent several risks associated…

Deep infiltrating endometriosis (DIE) is a severe condition frequently linked to infertility, yet the optimal integration of surgery and assisted reproductive technology (ART) remains controversial. This study reports two cases of infertili…

Uterine mesothelial cysts (UMCs) are rare, benign lesions that arise from the mesothelial lining of the uterus and are only sporadically documented in the literature. Because of their extremely low incidence, the clinical presentation and i…

BackgroundChronic enteropathy associated with solute carrier organic anion transporter family member 2A1 (SLCO2A1) (CEAS) is a rare autosomal recessive hereditary disease characterized by anemia, hypoproteinemia, abdominal pain, diarrhea, a…

Intracerebral hemorrhage (ICH) is a most serious type of hemorrhagic stroke with a continuously rising incidence globally, without effective cure available. The underlying mechanisms driving brain injury are complex and include inflammation…

OBJECTIVE: Clear cell borderline ovarian tumor is a rare subtype of borderline ovarian tumor for which the clinicopathological characteristics, management, and prognosis remain unclear. Herein, we describe the clinical features, treatment o…

Serous papillary adenofibroma (SPAF) is a rare benign tumor in gynecological practice. Most patients have no symptoms and occasionally present with pelvic masses during physical examinations. SPAF consists of both fibrous and epithelial par…

BackgroundClomiphene citrate effectively suppressed the negative feedback of estrogen on the hypothalamus and induces premature luteinizing hormone (LH) surge during controlled ovulation stimulation, while obese women often have impaired hy…