Israel Ortega

No ORCID on file · 4 papers in corpus · active 2012-2015

Study types

  • article 2
  • book-chapter 1
  • other 1

Condition tags

  • endometriosis 4
book-chapter 2015
Endometriosis and ART
·doi:10.5005/jp/books/12512_47
article 2013
Effects of Simvastatin on Retinoic Acid System in Primary Human Endometrial Stromal Cells and in a Chimeric Model of Human Endometriosis
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2012-3402

CONTEXT: Retinoic acid (RA) may promote survival or apoptosis of cells, depending on the levels of binding proteins: apoptosis-inducing cellular RA binding protein 2 (CRABP2), and cell survival-promoting fatty acid binding protein 5 (FABP5)…

other 2013
Resveratrol potentiates effect of simvastatin on inhibition of mevalonate pathway in human endometrial stromal cells
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2012-3387

CONTEXT: Growth of endometriotic lesions in rodent model of endometriosis is inhibited by resveratrol, a natural polyphenol with antiproliferative and antiinflammatory properties, and simvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl-…

article 2012
Simvastatin Decreases Invasiveness of Human Endometrial Stromal Cells1
Biology of reproduction ·doi:10.1095/biolreprod.111.098806

Recently we reported that statins, the competitive inhibitors of the key enzyme regulating the mevalonate pathway, 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR), decrease proliferation of human endometrial stromal (HES) cells. Fur…