Xueheng Zhao

No ORCID on file · 2 papers in corpus

lab-animal 2010

The chemopreventive action of equol enantiomers in a chemically induced animal model of breast cancer

Carcinogenesis ·doi:10.1093/carcin/bgq025

We describe for the first time the chemopreventive effects of S-(-)equol and R-(+)equol, diastereoisomers with contrasting affinities for estrogen receptors (ERs). S-(-)equol, a ligand for ERbeta, is an intestinally derived metabolite forme…

rct 2009

The pharmacokinetic behavior of the soy isoflavone metabolite S-(-)equol and its diastereoisomer R-(+)equol in healthy adults determined by using stable-isotope-labeled tracers

The American journal of clinical nutrition ·doi:10.3945/ajcn.2009.27981

BACKGROUND: The nonsteroidal estrogen equol occurs as diastereoisomers, S-(-)equol and R-(+)equol, both of which have significant biological actions. S-(-)equol, the naturally occurring enantiomer produced by 20-30% of adults consuming soy …