Fujihara M

No ORCID on file · 1 paper in corpus · active 2022
2022
Identification of a Vitamin-D Receptor Antagonist, MeTC7, which Inhibits the Growth of Xenograft and Transgenic Tumors In Vivo.
Journal of medicinal chemistry ·doi:10.1021/acs.jmedchem.1c01878

Vitamin-D receptor (VDR) mRNA is overexpressed in neuroblastoma and carcinomas of lung, pancreas, and ovaries and predicts poor prognoses. VDR antagonists may be able to inhibit tumors that overexpress VDR. However, the current antagonists …