Yi Kan Wang

No ORCID on file · 4 papers in corpus · active 2015-2017

Study types

  • article 3
  • other 1

Condition tags

  • mesh:D004715 3
  • endometriosis 3
article 2017
Abstract DPOC-014: BEYOND CODING MUTATIONS: USING RETROTRANSPOSONS TO PREDICT OVARIAN CANCER DEVELOPMENT
·doi:10.1158/1557-3265.ovcasymp16-dpoc-014

Abstract PURPOSE: Women with endometriosis, a painful condition caused by displaced endometrial tissue, have a 3-fold increased risk of developing endometrioid ovarian cancer (ENOC) and clear cell ovarian cancer (CCOC). How two distinct can…

other 2017
Genomic consequences of aberrant DNA repair mechanisms stratify ovarian cancer histotypes
Nature genetics ·doi:10.1038/ng.3849

We studied the whole-genome point mutation and structural variation patterns of 133 tumors (59 high-grade serous (HGSC), 35 clear cell (CCOC), 29 endometrioid (ENOC), and 10 adult granulosa cell (GCT)) as a substrate for class discovery in …

article 2017
LINE-1 retrotransposon-mediated DNA transductions in endometriosis associated ovarian cancers
Gynecologic oncology ·doi:10.1016/j.ygyno.2017.09.032
article 2015
Multifocal endometriotic lesions associated with cancer are clonal and carry a high mutation burden
The Journal of Pathology ·doi:10.1002/path.4516

Endometriosis is a significant risk factor for clear cell and endometrioid ovarian cancers and is often found contiguous with these cancers. Using whole-genome shotgun sequencing of seven clear cell ovarian carcinomas (CCC) and targeted seq…