Shu Zhu — Endo Lab

other 2026

The role of insulin-like growth factor binding proteins in TGF-β1-induced fibroblast-myofibroblast transition during endometriosis fibrosis

Cellular signalling ·doi:10.1016/j.cellsig.2026.112362

Fibrosis is a defining feature of endometriosis (EMS). Our previous single-cell RNA sequencing (scRNA-seq) revealed myofibroblasts (MFBs) as the predominant cells in ectopic endometrium (ECE), mainly derived from fibroblast-to-myofibroblast…

preprint 2023

Efficacy and safety of dienogest versus GnRH-a combined with dienogest therapy for adenomyosis

·doi:10.21203/rs.3.rs-3509174/v1

Abstract Objective To investigate the efficacy and safety of dienogest((DNG) monotherapy and gonadotropin-releasing hormone agonist (GnRH-a) combined with DNG sequential treatment for adenomyosis. Methods This is a retrospective study.15…

article 2023

Laparoscopic Single-site Surgery for Resection of Abdominal Wall Endometriosis

Journal of minimally invasive gynecology ·doi:10.1016/j.jmig.2023.02.011

article 2022

The Characteristics of Myofibroblasts and Pericytes in Endometriosis During Secretory Phase Revealed by Single-Cell RNA-Sequencing

·doi:10.2139/ssrn.4147538

article 2022

The heterogeneity of fibrosis and angiogenesis in endometriosis revealed by single-cell RNA-sequencing

Biochimica et biophysica acta. Molecular basis of disease ·doi:10.1016/j.bbadis.2022.166602

Fibrosis, angiogenesis and chronic inflammation are the inherent characteristics of endometriosis (EMS). The cellular heterogeneity of ectopic and non-ectopic endometrium by single-cell RNA-sequencing (scRNA-seq)at secretory phase without t…

article 2021

Multi‐omics analysis reveals the interaction between the complement system and the coagulation cascade in the development of endometriosis

Scientific reports ·doi:10.1038/s41598-021-90112-x

Endometriosis (EMS) is a disease that shows immune dysfunction and chronic inflammation characteristics, suggesting a role of complement system in its pathophysiology. To find out the hub genes and pathways involved in the pathogenesis of E…