Tsolova AO

ORCID: 0000-0002-0273-5815 · 3 papers in corpus
2025
Active chromatin marks and up-regulation of FOXC1 in uterine epithelial cells demarcate the onset of reproductive decline in aging females.
NAR molecular medicine ·doi:10.1093/narmme/ugaf031

Advanced maternal age increases the risk of pregnancy complications due, in part, to changes in the uterine environment. Here, we show that uterine aging in mice is associated with a progressive increase in transcriptional variation, accomp…

2023
Ulipristal acetate versus levonorgestrel-releasing intrauterine system for heavy menstrual bleeding: the UCON randomised controlled trial and mechanism of action study

BackgroundHeavy menstrual bleeding affects one in four women and negatively impacts quality of life. The levonorgestrel-releasing intrauterine system is an effective long-term treatment but is discontinued by many due to unpredictable bleed…

review 2022
Pre-clinical models to study abnormal uterine bleeding (AUB)
EBioMedicine ·doi:10.1016/j.ebiom.2022.104238

Abnormal Uterine Bleeding (AUB) is a common debilitating condition that significantly reduces quality of life of women across the reproductive age span. AUB creates significant morbidity, medical, social, and economic problems for women, th…