Tsolova AO

Background Abnormal uterine bleeding (AUB) is commonly managed as a single clinical entity with standardised pathways. However, high therapeutic failure and subsequent hysterectomy rates indicate AUB is not a single symptom. AUB affects ov…

Advanced maternal age increases the risk of pregnancy complications due, in part, to changes in the uterine environment. Here, we show that uterine aging in mice is associated with a progressive increase in transcriptional variation, accomp…

BackgroundHeavy menstrual bleeding affects one in four women and negatively impacts quality of life. The levonorgestrel-releasing intrauterine system is an effective long-term treatment but is discontinued by many due to unpredictable bleed…

Abnormal Uterine Bleeding (AUB) is a common debilitating condition that significantly reduces quality of life of women across the reproductive age span. AUB creates significant morbidity, medical, social, and economic problems for women, th…