S Gobec
No ORCID on file
· 5 papers in corpus
· active 2008-2011
Study types
- other 3
- review 2
Condition tags
- endometriosis 5
Top journals
Frequent coauthors
- T Lanišnik Rižner 4
- P Brožič 3
- C W G Fishwick 1
- G Hribar 1
- J Cesar 1
- M Davies 1
- A P Johnson 1
- P Kocbek 1
- S Starčević 1
- S Turk 1
other
2011
Human 17β-hydroxysteroid dehydrogenase (17β-HSD) type 1 is an enzyme that acts at the pre-receptor level. It catalyzes the NADPH-dependent reduction of the weak estrogen estrone into the most potent estrogen 17β-estradiol, which exerts prol…
review
2011
The AKR1C aldo-keto reductases (AKR1C1-AKR1C4) are enzymes that interconvert steroidal hormones between their active and inactive forms. In this manner, they can regulate the occupancy and trans-activation of the androgen, estrogen and prog…
other
2011
The human aldo-keto reductases 1C1 and 1C3 (AKR1C1 and AKR1C3) are important 20-ketosteroid reductases in pre-receptor regulation of progesterone action. Both AKR1C1 and AKR1C3 convert progesterone to the less potent metabolite 20α-hydroxyp…
other
2009
Human hydroxysteroid dehydrogenase (HSD) AKR1C1 is a member of the aldo-keto reductase superfamily, and it functions mainly as a 20alpha-HSD. It catalyzes the reduction of the potent progesterone to the weak 20alpha-hydroxyprogesterone, and…
review
2008
Carcinogenesis of hormone-related cancers involves hormone-stimulated cell proliferation, which increases the number of cell divisions and the opportunity for random genetic errors. In target tissues, steroid hormones are interconverted bet…