Vijayachitra Modhukur

ORCID: 0000-0002-7123-9903 · 27 papers in corpus · active 2016-2024

Study types

  • dataset 12
  • other 9
  • article 3
  • preprint 2
  • review 1

Condition tags

  • endometriosis 25
  • mesh:D004715 5
  • chronic_pelvic_pain 1
  • infertility 1
other 2024
Communications biology ·doi:10.1038/s42003-024-06713-5

Current therapeutics of endometriosis focus on hormonal disruption of endometriotic lesions (ectopic endometrium, EcE). Recent findings show higher glycolysis utilization in EcE, suggesting non-hormonal strategy for disease treatment that a…

preprint 2024
·doi:10.1101/2024.02.27.580606

Abstract Current therapeutics of endometriosis are limited to hormonal action on endometriotic lesions to disrupt their growth. Based on the recent findings of the high utilization of glycolysis over oxidative metabolism (Warburg-like effec…

other 2024
Frontiers in endocrinology ·doi:10.3389/fendo.2024.1465393

BACKGROUND: Endometriosis is characterized by the ectopic growth of endometrial-like cells, causing chronic pelvic pain, adhesions and impaired fertility in women of reproductive age. Usually, these lesions grow in the peritoneal cavity in …

review 2024
Endocrinology ·doi:10.1210/endocr/bqae110

Stanniocalcin (STC) 1 and 2 serve as antihyperglycemic polypeptide hormones with critical roles in regulating calcium and phosphate homeostasis. They additionally function as paracrine and/or autocrine factors involved in numerous physiolog…

article 2023
Journal of medical Internet research ·doi:10.2196/45381

BACKGROUND: Endometriosis is a debilitating and difficult-to-diagnose gynecological disease. Owing to limited information and awareness, women often rely on social media platforms as a support system to engage in discussions regarding their…

article 2022
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2022.05.028
preprint 2022
·doi:10.2196/preprints.45381

BACKGROUND Endometriosis is a debilitating and difficult-to-diagnose gynecological disease. Owing to limited information and awareness, women often rely on social media platforms as a support system to engage in discussions regarding their…

other 2017
Scientific reports ·doi:10.1038/s41598-017-03682-0

The inner uterine lining (endometrium) is a unique tissue going through remarkable changes each menstrual cycle. Endometrium has its characteristic DNA methylation profile, although not much is known about the endometrial methylome changes …

other 2016
·doi:10.6084/m9.figshare.c.3641012_d4

Principal component analysis describing DNA methylation data across all studied endometrial samples. The large dots and triangles mark overlapping samples. (TIF 852 kb)

other 2016
·doi:10.6084/m9.figshare.c.3641012_d4.v1

Principal component analysis describing DNA methylation data across all studied endometrial samples. The large dots and triangles mark overlapping samples. (TIF 852 kb)

dataset 2016
·doi:10.6084/m9.figshare.c.3641012_d5

Differentially methylated regions between women with endometriosis and healthy women. The methylation data of all patients was compared to controls. Menstrual cycle day has not been taken into account. (XLSX 15 kb)

dataset 2016
·doi:10.6084/m9.figshare.c.3641012_d5.v1

Differentially methylated regions between women with endometriosis and healthy women. The methylation data of all patients was compared to controls. Menstrual cycle day has not been taken into account. (XLSX 15 kb)

dataset 2016
·doi:10.6084/m9.figshare.c.3641012_d7

Differentially methylated regions between different menstrual cycle phases. The methylation data of each menstrual cycle phase was compared to other phases. (XLSX 2676 kb)

dataset 2016
·doi:10.6084/m9.figshare.c.3641012_d7.v1

Differentially methylated regions between different menstrual cycle phases. The methylation data of each menstrual cycle phase was compared to other phases. (XLSX 2676 kb)

dataset 2016
·doi:10.6084/m9.figshare.c.3641012_d1.v1

Functional annotation clustering of hypo- and hypermethylated genes in endometrial tissue using g:profiler bioinformatics tool. The complete lists of DMRs between different menstrual cycle phases was used to create the lists of Gene Ontolog…

dataset 2016
·doi:10.6084/m9.figshare.c.3641012_d1

Functional annotation clustering of hypo- and hypermethylated genes in endometrial tissue using g:profiler bioinformatics tool. The complete lists of DMRs between different menstrual cycle phases was used to create the lists of Gene Ontolog…

dataset 2016
·doi:10.6084/m9.figshare.c.3641012_d2.v1

Pathway analysis of hypo- and hypermethylated genes in endometrial tissue using g:profiler bioinformatics tool. The complete lists of DMRs between different menstrual cycle phases was used to create the list of Kyoto Encyclopedia of Genes a…

dataset 2016
·doi:10.6084/m9.figshare.c.3641012_d2

Pathway analysis of hypo- and hypermethylated genes in endometrial tissue using g:profiler bioinformatics tool. The complete lists of DMRs between different menstrual cycle phases was used to create the list of Kyoto Encyclopedia of Genes a…

other 2016
·doi:10.6084/m9.figshare.c.3641012_d6.v1

Venn diagrams of differentially methylated genes. Diagrams show the total number of hypo- and hypermethylated genes identified in each comparison. (TIF 3142 kb)

other 2016
·doi:10.6084/m9.figshare.c.3641012_d6

Venn diagrams of differentially methylated genes. Diagrams show the total number of hypo- and hypermethylated genes identified in each comparison. (TIF 3142 kb)

dataset 2016
·doi:10.6084/m9.figshare.c.3641012_d3

Menstrual cycle phase specific genes. The list of late-secretory and menstrual phase specific hyper- and hypomethylated genes. (XLSX 28 kb)

dataset 2016
·doi:10.6084/m9.figshare.c.3641012_d3.v1

Menstrual cycle phase specific genes. The list of late-secretory and menstrual phase specific hyper- and hypomethylated genes. (XLSX 28 kb)

dataset 2016
·doi:10.6084/m9.figshare.c.3641012_d8.v1

PCR primers used in the methylation validation analysis. PCR primers for the bisulfite-treated DNA were designed using MethPrimer[42]. (XLSX 9 kb)

dataset 2016
·doi:10.6084/m9.figshare.c.3641012_d8

PCR primers used in the methylation validation analysis. PCR primers for the bisulfite-treated DNA were designed using MethPrimer[42]. (XLSX 9 kb)

article 2016
Clinical epigenetics ·doi:10.1186/s13148-015-0168-z

BACKGROUND: Alterations in endometrial DNA methylation profile have been proposed as one potential mechanism initiating the development of endometriosis. However, the normal endometrial methylome is influenced by the cyclic hormonal changes…