T J Rutherford

No ORCID on file · 2 papers in corpus

lab-animal 2010

hI-con1, a factor VII-IgGFc chimeric protein targeting tissue factor for immunotherapy of uterine serous papillary carcinoma

British journal of cancer ·doi:10.1038/sj.bjc.6605760

BACKGROUND: Uterine serous papillary adenocarcinoma (USPC) is a highly aggressive variant of endometrial cancer. Human immuno-conjugate molecule (hI-con1) is an antibody-like molecule targeted against tissue factor (TF), composed of two hum…

observational 2007

IGF-II promoter methylation and ovarian cancer prognosis

Journal of cancer research and clinical oncology ·doi:10.1007/s00432-007-0211-3

PURPOSE: The insulin-like growth factor-II (IGF-II) gene has four promoters that produce distinct transcripts which vary by tissue type and developmental stage. Dysregulation of normal promoter usage has been shown to occur in cancer; DNA m…