Bryja A

ORCID: 0000-0002-4338-8119 · 7 papers in corpus · active 2019-2026
2026
Cancer cell international ·doi:10.1186/s12935-026-04197-3

PVT1 is a non-coding RNA (ncRNA) playing an important role in various biological processes, including cell survival, differentiation, proliferation, and chromatin regulation. Overexpression of PVT1 improve a proliferation rate even for 30% …

2025
International journal of molecular sciences ·doi:10.3390/ijms262411942

During oocyte maturation, granulosa cells (GCs) respond to fluctuating hormone levels in the ovary. The study aims to reveal metabolism and activity patterns of isolated and cultured GCs, reflecting in vivo processes. A downregulation of GA…

2024
International journal of molecular sciences ·doi:10.3390/ijms25137109

The oviduct provides an optimal environment for the final preparation, transport, and survival of gametes, the fertilization process, and early embryonic development. Most of the studies on reproduction are based on in vitro cell culture mo…

2024
Frontiers in oncology ·doi:10.3389/fonc.2024.1418005

Endometrial cancer (EC) is one of the most common gynecologic cancers. In recent years, research has focused on the genetic characteristics of the tumors to detail their prognosis and tailor therapy. In the case of EC, genetic mutations hav…

2020
Journal of clinical medicine ·doi:10.3390/jcm9062006

Granulosa cells (GCs) have many functions and are fundamental for both folliculogenesis and oogenesis, releasing hormones and communicating directly with the oocyte. Long-term in vitro cultures of GCs show significant stem-like characterist…

2019
Histochemistry and cell biology ·doi:10.1007/s00418-018-1750-1

The human ovarian granulosa cells (GCs) surround the oocyte and form the proper architecture of the ovarian follicle. The ability of GCs to proliferate and differentiate in the conditions of in vitro culture has been proven. However, there …

2019
Molecular medicine reports ·doi:10.3892/mmr.2019.9837

Granulosa cells (GCs) have many functions in the endocrine system. Most notably, they produce progesterone following ovulation. However, it has recently been proven that GCs can change their properties when subjected to long‑term culture. I…