Gründker C

ORCID: 0000-0001-8828-7955 · 3 papers in corpus
2022
Like Brothers in Arms: How Hormonal Stimuli and Changes in the Metabolism Signaling Cooperate, Leading HPV Infection to Drive the Onset of Cervical Cancer.
International journal of molecular sciences ·doi:10.3390/ijms23095050

Despite all precautionary actions and the possibility of using vaccinations to counteract infections caused by human papillomaviruses (HPVs), HPV-related cancers still account for approximately 5% of all carcinomas. Worldwide, many women ar…

2021
The Role of Gonadotropin-Releasing Hormone (GnRH) in Endometrial Cancer.
Cells ·doi:10.3390/cells10020292

Endometrial cancer (EC) is one of the most common gynecological malignancies. Gonadotropin releasing hormone (GnRH) is a decapeptide first described to be secreted by the hypothalamus to regulate pituitary gonadotropin secretion. In this sy…

2010
Gonadotropin-releasing hormone type II antagonist induces apoptosis in MCF-7 and triple-negative MDA-MB-231 human breast cancer cells in vitro and in vivo.
Breast cancer research : BCR ·doi:10.1186/bcr2606

IntroductionTriple-negative breast cancer does not express estrogen and progesterone receptors, and no overexpression/amplification of the HER2-neu gene occurs. Therefore, this subtype of breast cancer lacks the benefits of specific therapi…