Bo L

No ORCID on file · 8 papers in corpus · active 2013-2025

Condition tags

  • dysmenorrhea 2
2025
Chlorogenic Acid Ameliorates Chronic Unpredictable Stress-Induced Diminished Ovarian Reserve Through Ovarian Renin-Angiotensin System.
Molecular nutrition & food research ·doi:10.1002/mnfr.202400814

Chronic stress could impair ovarian reserve through hyperactivation of the hypothalamic-pituitary-adrenal (HPA) axis, leading to reduced oocyte quality and endocrine dysfunction. The ovarian renin-angiotensin system (OVRAS) modulates follic…

2024
Analysis of gene expression difference and biological process in chorionic villi of unexplained recurrent spontaneous abortion.
BMC pregnancy and childbirth ·doi:10.1186/s12884-024-07099-2

ObjectiveTo explore the biological relationship between the regulatory signal pathways involved in differentially expressed genes and recurrent spontaneous abortion (RSA) by analyzing the gene expression microarray data of unexplained RSA.M…

2024
Identification of somatic mutation-driven enhancers and their clinical utility in breast cancer.
iScience ·doi:10.1016/j.isci.2024.108780

Somatic mutations contribute to cancer development by altering the activity of enhancers. In the study, a total of 135 mutation-driven enhancers, which displayed significant chromatin accessibility changes, were identified as candidate risk…

2024
LncRNA HOTAIR regulates autophagy and proliferation mechanisms in premature ovarian insufficiency through the miR-148b-3p/ATG14 axis.
Cell death discovery ·doi:10.1038/s41420-024-01811-z

Premature ovarian insufficiency (POI) is a serious disease significantly affecting the physical and mental health of women of reproductive age, not just impacting fertility outcomes. Ovarian damage due to chemotherapy remains a major cause …

2024
Transplantation of human umbilical cord-derived mesenchymal stem cells improves age-related ovarian functional decline via regulating the local renin-angiotensin system on inflammation and oxidative stress.
Stem cell research & therapy ·doi:10.1186/s13287-024-03997-6

BackgroundAge-related reproductive aging is a natural and irreversible physiological process, and delaying childbearing is increasingly common all over the world. Transplantation of mesenchymal stem cells (MSCs) is considered a new and effe…

2017
Moxibustion for pain relief in patients with primary dysmenorrhea: A randomized controlled trial.
PloS one ·doi:10.1371/journal.pone.0170952

BackgroundThough moxibustion is frequently used to treat primary dysmenorrhea in China, relevant evidence supporting its effectiveness is still scanty.MethodsThis study was a pragmatic randomized, conventional drug controlled, open-labeled …

2014
Effectiveness study of moxibustion on pain relief in primary dysmenorrhea: study protocol of a randomized controlled trial.
Evidence-based complementary and alternative medicine : eCAM ·doi:10.1155/2014/434978

Dysmenorrhea is a prevalent problem in menstruating women. As a nonpharmacologic and free of relevant side effects intervention, moxibustion is considered as a safe treatment and has long been recommended for dysmenorrhea in China. However,…

2013
Expression and significance of lysyl oxidase-like 1 and fibulin-5 in the cardinal ligament tissue of patients with pelvic floor dysfunction.
Journal of biomedical research ·doi:10.7555/jbr.27.20110142

Pelvic organ prolapse (POP) is a disabling disorder in women characterized by a loss of pelvic floor support, leading to the herniation of the uterus into or through the vagina. POP is a complex problem that likely involves multiple mechani…