Maya L. Seshan — Endo Lab

article 2026

Transcriptome differences in lesions by color, and cancer mutations in endometriosis

Reproduction & fertility ·doi:10.1530/raf-26-0057

ABSTRACT: Endometriosis is a disease where cells similar to those of the uterine lining grow outside of the uterus, embedding into tissues and organs in the abdominal cavity, forming lesions and causing pain and infertility. Previous studie…

article 2025

Endometriosis and the Risk of Adnexal Torsion

·doi:10.1177/10424067251408807

Study Objective: This study aims to determine if the presence of endometriosis decreases the probability of adnexal torsion. We hypothesize that the presence of endometriosis is associated with a lower risk of ovarian torsion. Methods: A re…

article 2024

11360 Endometriosis and the Risk of Adnexal Torsion

·doi:10.1016/j.jmig.2024.09.739

other 2024

Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in mice

Science translational medicine ·doi:10.1126/scitranslmed.adk8230

Endometriosis is a debilitating and painful gynecological inflammatory disease affecting up to 15% of women and transgender men. Current treatments are ineffective for a substantial proportion of patients, underscoring the need for addition…

article 2023

DIFFERENTIAL TRANSCRIPTIONAL PROFILES IN PHENOTYPICALLY DISTINCT ENDOMETRIOSIS LESIONS SHOW INCREASED LYMPHOCYTE ACTIVITY, CYTOKINE PRODUCTION, AND INFLAMMATORY MARKERS IN RED LESIONS

·doi:10.1016/j.fertnstert.2023.08.652

preprint 2023

Nociceptor to macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth

·doi:10.1101/2023.08.28.555101

Abstract Endometriosis is a debilitating and painful gynecological inflammatory disease affecting approximately 15% of women. Current treatments are ineffective for a significant fraction of patients, underscoring the need for new medical t…