Hamit Hakan

ORCID: 0000-0002-9202-4944 · 3 papers in corpus · active 2017-2023

Study types

  • article 3
article 2023
The Effects of Some Phosphodiesterase 5 Inhibitors on Oxidative Stress, VEGF, BMP 2 and 9 in the Liver Tissue of Ovariectomized Rats
·doi:10.5505/vtd.2023.90757

Introduction:Osteoporosis is an important health problem and there is no effective treatment yet.phosphodiesterase 5 inhibitors are promising agents for the treatment of osteoporosis.In this study, we aimed to determine the effects of phosp…

article 2020
Stimulating effects of vardenafil, tadalafil, and udenafil on vascular endothelial growth factor, angiogenesis, vitamin D3, bone morphogenic proteins in ovariectomized rats
·doi:10.1080/13813455.2020.1755695

Objective This study investigated the effect of vardenafil, tadalafil, and udenafil from phosphodiesterase-5 inhibitors (PDE-5Is) on bone morphogenic-protein (BMP)2 and 4 levels, along with angiogenesis in ovariectomized rat’s kidney.Method…

article 2017
The effect of PDE5 inhibitors on bone and oxidative damage in ovariectomy-induced osteoporosis
·doi:10.1177/1535370217703352

Osteoporosis is a major public health problem associated with many factors, and it affects more than 50% of women over 50 years old. In the current study, our purpose was to investigate the effects of phosphodiestarase-5 inhibitors on osteo…