Misfeldt ML — Endo Lab

2005

17Beta-estradiol suppresses TLR3-induced cytokine and chemokine production in endometrial epithelial cells.

Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-3-74

BackgroundThe human endometrium is an important site for contact between the host and pathogens ascending the reproductive tract, and thus plays an important role in female reproductive tract immunity. Previous work in our laboratory has su…

2005

Human endometrial epithelial cells cyclically express Toll-like receptor 3 (TLR3) and exhibit TLR3-dependent responses to dsRNA.

Human immunology ·doi:10.1016/j.humimm.2004.12.003

Toll-like receptor 3 (TLR3) responds to dsRNA, a product of most viral life cycles, and initiates production of proinflammatory and antiviral cytokines. The role of TLR3 in human mucosal immunity of the endometrium has not been examined. Th…

2004

Expression of Toll-like receptors in human endometrial epithelial cells and cell lines.

American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.1600-0897.2004.00189.x

ProblemAre toll-like receptors (TLRs) expressed by human endometrium and endometrial cell lines?Methods of studyExpression of each TLR mRNA species was determined by reverse transcriptase-polymerase chain reaction (RT-PCR) analysis of proli…