Janice Rymer

Purpose: We performed a retrospective audit of General Practitioners' (GPs) referrals to the specialist Menopause Clinic at Guys and St Thomas's (GSTT) between 2021 and 2022. We aim to establish the indication for the referrals and whether …

Obesity is a problem of enormous proportions in the UK and worldwide. Projections by the World Health Organization and UK-based research predict that 74% of men and 64% of women in the UK will be overweight by 2030.1 Obesity has significant…

CONTEXT: Women with premature ovarian failure (POF) face many years of estrogen deficiency. One of the major consequences is bone loss. The optimal form of estrogen replacement is unknown and management is not evidence based. The 2 broad op…

Medical management of endometriosis and fibroids involves manipulation of the hypothalamic-pituitary-gonadal axis to alter the balance of sex hormones thereby inhibiting disease progression and ameliorate symptoms. Unfortunately, resultant …

This service evaluation aimed to characterise the referrals to the premature ovarian failure clinic, including the type of referral and patient needs, in order to plan for future service provision. The majority of women seen in the clinic e…

Gonadotrophin receptor hormone analogues (GnRHa) have been used in a range of sex hormone-dependent disorders. In the management of premenstrual syndrome, they can completely abolish symptoms. The success of GnRHa in the treatment of endome…

The authors present a case of a 51-year-old woman with endometriosis who developed immune thrombocytopenic purpura. Her platelets dropped to 2×10(9)/l, and she had haemorrhage into her right endometrioma causing a large pelvic haematoma. Sh…

Premature ovarian failure is a relatively common clinical condition, and carries important long-term health consequences. Estrogen replacement is recommended to alleviate unpleasant hypo-estrogenic symptoms and reduce long-term health risks…

SECTION 1: HISTORY TAKING AND EXAMINATION IN OBSTETRICS AND GYNAECOLOGY 1. Gynaecology history taking. 2. Gynaecological examination. 3. Obstetric history taking. 4. Obstetric examination. SECTION 2: GYNAECOLOGY 5. The menstrual cycle, mens…

(2000). Which is the appropriate hormone replacement therapy after sub-total hysterectomy? Climacteric: Vol. 3, No. 1, pp. 65-67.

OBJECTIVES: To assess the effects of six years tibolone therapy on the genital tract in postmenopausal women against matched voluntary controls. DESIGN: Prospective, non-randomised, open label study of the efficacy of tibolone. METHODS: S…