Xiruo Zhang

No ORCID on file · 2 papers in corpus

lab-animal 2021

Treg deficiency-mediated TH 1 response causes human premature ovarian insufficiency through apoptosis and steroidogenesis dysfunction of granulosa cells

Clinical and translational medicine ·doi:10.1002/ctm2.448

Immune dysregulation has long been proposed as a component of premature ovarian insufficiency (POI), but the underlying mediators and mechanisms remain largely unknown. Here we showed that patients with POI had augmented T helper 1 (TH 1) r…

observational 2020

Dysregulated cytokine profile associated with biochemical premature ovarian insufficiency

American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.13292

PROBLEM: Premature ovarian insufficiency (POI) imposes great challenge on female reproduction. Whether immune disturbance in ovarian environment was implicated in POI remains unclear. We aimed to characterize the cytokine profile in follicu…