Brossard M

ORCID: 0000-0003-4144-3978 · 3 papers in corpus
2020
Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma.
Nature communications ·doi:10.1038/s41467-020-16590-1

Genome-wide association studies (GWAS) have identified ~20 melanoma susceptibility loci, most of which are not functionally characterized. Here we report an approach integrating massively-parallel reporter assays (MPRA) with cell-type-speci…

2015
Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma.
Nature genetics ·doi:10.1038/ng.3373

Thirteen common susceptibility loci have been reproducibly associated with cutaneous malignant melanoma (CMM). We report the results of an international 2-stage meta-analysis of CMM genome-wide association studies (GWAS). This meta-analysis…

2014
The effect on melanoma risk of genes previously associated with telomere length.
Journal of the National Cancer Institute ·doi:10.1093/jnci/dju267

Telomere length has been associated with risk of many cancers, but results are inconsistent. Seven single nucleotide polymorphisms (SNPs) previously associated with mean leukocyte telomere length were either genotyped or well-imputed in 111…