Jorge S. Reis‐Filho

ORCID: 0000-0003-2969-3173 · 3 papers in corpus
preprint 2023
Data from PI3K Pathway Dependencies in Endometrioid Endometrial Cancer Cell Lines
·doi:10.1158/1078-0432.c.6522264

AbstractPurpose: Endometrioid endometrial cancers (EEC) frequently harbor coexisting mutations in phosphoinositide 3-kinase (PI3K) pathway genes, including PTEN, PIK3CA, PIK3R1, and KRAS. We sought to define the genetic determinants of PI3K…

preprint 2023
Data from PI3K Pathway Dependencies in Endometrioid Endometrial Cancer Cell Lines
·doi:10.1158/1078-0432.c.6522264.v1

AbstractPurpose: Endometrioid endometrial cancers (EEC) frequently harbor coexisting mutations in phosphoinositide 3-kinase (PI3K) pathway genes, including PTEN, PIK3CA, PIK3R1, and KRAS. We sought to define the genetic determinants of PI3K…

2021
Clonal relationship and directionality of progression of synchronous endometrial and ovarian carcinomas in patients with DNA mismatch repair-deficiency associated syndromes.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc ·doi:10.1038/s41379-020-00721-6

Sporadic synchronous endometrial (ECs) and ovarian cancers (OCs), although clinically considered to be independent primaries, have been shown to be clonally related and likely constitute metastases from each other. We sought to define wheth…