Shuaishuai Guo

No ORCID on file · 3 papers in corpus
lab-animal 2026
Mechanism and Intervention of the NPY1R/CREB Signaling Axis in Regulating Inflammatory Response in Aged Ovarian Granulosa Cells and Ovarian Senescence
FASEB journal : official publication of the Federation of American Societies for Experimental Biology ·doi:10.1096/fj.202601614r

Ovarian senescence is accompanied by inflammatory responses, yet the underlying mechanism remains incompletely elucidated. In this study, transcriptome sequencing was performed on ovarian granulosa cells from advanced-age patients and norma…

lab-animal 2026
NR4A1-Driven Granulosa Cell Ferroptosis Contributes to Obesity-Related Ovarian Dysfunction and Metformin-Mediated Ovarian Protection
FASEB journal : official publication of the Federation of American Societies for Experimental Biology ·doi:10.1096/fj.202603415r

Obesity triggers ovarian dysfunction and female infertility accompanied by granulosa cell damage. Ferroptosis, iron-dependent lipid peroxidation-mediated cell death, participates in multiple reproductive diseases, yet the molecular cascade …

observational 2019
Resilience acts as a moderator in the relationship between infertility-related stress and fertility quality of life among women with infertility: a cross-sectional study
Health and quality of life outcomes ·doi:10.1186/s12955-019-1099-8

BACKGROUND: Infertility-related stress can seriously impact the fertility quality of life (QoL) of infertile women. Resilience, as a coping resource, can effectively combat psychological stress. This study aimed to evaluate the fertility Qo…