Dhagat U

ORCID: 0000-0002-5650-5767 · 1 paper in corpus

other 2007

A salicylic acid-based analogue discovered from virtual screening as a potent inhibitor of human 20alpha-hydroxysteroid dehydrogenase

Medicinal chemistry (Shariqah (United Arab Emirates)) ·doi:10.2174/157340607782360399

20alpha-hydroxysteroid dehydrogenase (AKR1C1) plays a key role in the metabolism of progesterone and other steroid hormones, thereby regulating their action at the pre-receptor level. AKR1C1 is implicated in neurological and psychiatric con…