Sandrine Marchais-Oberwinkler (189194)

No ORCID on file · 1 paper in corpus · active 2016

Study types

  • article 1
article 2016
Lead Optimization of 17β-HSD1\nInhibitors of\nthe (Hydroxyphenyl)naphthol Sulfonamide Type for the Treatment of\nEndometriosis
·doi:10.1021/jm201735j.s001

The reduction of estrone to estradiol, the most potent\nestrogen\nin human, is catalyzed by 17β-hydroxysteroid dehydrogenase type\n1 (17β-HSD1). A promising approach for the treatment of estrogen-dependent\ndiseases is the reduction of intr…