Ciro Isidoro

ORCID: 0000-0002-5494-3034 · 3 papers in corpus
2025
The Biological Role and Clinical Significance of BECLIN-1 in Cancer
·doi:10.20944/preprints202507.2396.v1

BECLIN-1 is a multidomain protein that through dynamic interaction with a variety of partners controls autophagy and apoptosis, two processes dysregulated in cancer cells, thus playing a crucial role in cell destiny. Mutations of BECN1 gene…

2022
A Novel Xeno-Free Method to Isolate Human Endometrial Mesenchymal Stromal Cells (E-MSCs) in Good Manufacturing Practice (GMP) Conditions.
International journal of molecular sciences ·doi:10.3390/ijms23041931

The cyclic regeneration of human endometrium is guaranteed by the proliferative capacity of endometrial mesenchymal stromal cells (E-MSCs). Due to this, the autologous infusion of E-MSCs has been proposed to support endometrial growth in a …

2018
The metabolic cross-talk between epithelial cancer cells and stromal fibroblasts in ovarian cancer progression: Autophagy plays a role.
Medicinal research reviews ·doi:10.1002/med.21473

Cancer and stromal cells, which include (cancer-associated) fibroblasts, adipocytes, and immune cells, constitute a mixed cellular ecosystem that dynamically influences the behavior of each component, creating conditions that ultimately fav…