Maria Lycke

ORCID: 0000-0002-1371-4649 · 3 papers in corpus
article 2021
Consideration should be given to smoking, endometriosis, renal function (eGFR) and age when interpreting CA125 and HE4 in ovarian tumor diagnostics
Clinical chemistry and laboratory medicine ·doi:10.1515/cclm-2021-0510

OBJECTIVES: To evaluate the impact of different biologic, histopathologic and lifestyle factors on serum levels of human epididymis protein 4 (HE4) and Cancer antigen 125 (CA125) in the diagnostic work up of women with an ovarian cyst or pe…

2018
A two-step strategy for identification of plasma protein biomarkers for endometrial and ovarian cancer.
Clinical proteomics ·doi:10.1186/s12014-018-9216-y

BackgroundOver 500,000 women worldwide are diagnosed with ovarian or endometrial cancer each year. We have used a two-step strategy to identify plasma proteins that could be used to improve the diagnosis of women with an indication of gynec…

2018
Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers.
Science translational medicine ·doi:10.1126/scitranslmed.aap8793

We report the detection of endometrial and ovarian cancers based on genetic analyses of DNA recovered from the fluids obtained during a routine Papanicolaou (Pap) test. The new test, called PapSEEK, incorporates assays for mutations in 18 g…